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Molecular clouds (MCs) are active sites of star formation in galaxies, and their formation and evolution are largely affected by stellar feedback. This includes outflows and winds from newly formed stars, radiation from young clusters, and supernova explosions. High-resolution molecular line observations allow for the identification of individual star-forming regions and the study of their integrated properties. Moreover, state-of-the-art simulations are now capable of accurately replicating the evolution of MCs, including all key stellar feedback processes. We present¹³CO(2–1) synthetic observations of the STARFORGE simulations produced using the radiative transfer code RADMC-3D, matching the observational setup of the SEDIGISM survey. From these synthetic observations, we identified the population of MCs using hierarchical clustering and analysed them to provide insights into the interpretation of observed MCs as they evolve. The flux distributions of the post-processed synthetic observations and the properties of the MCs, namely, radius, mass, velocity dispersion, virial parameter, and surface density, are consistent with those of SEDIGISM. Both samples of MCs occupy the same regions in the scaling relation plots; however, the average distributions of MCs at different evolutionary stages do not overlap on the plots. This highlights the reliability of our approach in modelling SEDIGISM and suggests that MCs at different evolutionary stages contribute to the scatter in observed scaling relations. We study the trends in MC properties, morphologies, and fragmentation over time to analyse their physical structure as they form, evolve, and are destroyed. MCs appear as small diffuse cloudlets in early stages, and this is followed by their evolution to filamentary structures before being shaped by stellar feedback into 3D bubbles and getting dispersed. These trends in the observable properties of MCs are consistent with other realisations of simulations and provide strong evidence that clouds exhibit distinct morphologies over the course of their evolution. 

Stars form in dense cores within molecular clouds, and newly formed stars influence their natal environments. How stellar feedback impacts core properties and evolution has been the subject of extensive investigation. We performed a hierarchical clustering (dendrogram) analysis of a STARFORGE (STAR FORmation in Gaseous Environments) simulation, modelling a giant molecular cloud to identify gas overdensities (cores) and study changes in their radius, mass, velocity dispersion, and virial parameter with respect to stellar feedback. We binned these cores on the basis of the fraction of gas affected by protostellar outflows, stellar winds, and supernovae and analysed the property distributions for each feedback bin. We find that cores that experience more feedback influence are smaller. Feedback notably enhances the velocity dispersion and virial parameter of the cores, more so than it reduces their radius. This is also evident in the linewidth–size relation, according to which cores in higher-feedback bins exhibit higher velocities than their similarly sized pristine counterparts. We conclude that stellar feedback mechanisms, which impart momentum to the molecular cloud, simultaneously compress and disperse the dense molecular gas. 

The morphology of the Milky Way is still a matter of debate. In order to shed light on uncertainties surrounding the structure of the Galaxy, in this paper, we study the imprint of spiral arms on the distribution and properties of its molecular gas. To do so, we take full advantage of the SEDIGISM (Structure, Excitation, and Dynamics of the Inner Galactic Interstellar Medium) survey that observed a large area of the inner Galaxy in the 13 CO (2–1) line at an angular resolution of 28′′. We analyse the influences of the spiral arms by considering the features of the molecular gas emission as a whole across the longitude–velocity map built from the full survey. Additionally, we examine the properties of the molecular clouds in the spiral arms compared to the properties of their counterparts in the inter-arm regions. Through flux and luminosity probability distribution functions, we find that the molecular gas emission associated with the spiral arms does not differ significantly from the emission between the arms. On average, spiral arms show masses per unit length of ~10 5 –10 6 M ⊙ kpc −1 . This is similar to values inferred from data sets in which emission distributions were segmented into molecular clouds. By examining the cloud distribution across the Galactic plane, we infer that the molecular mass in the spiral arms is a factor of 1.5 higher than that of the inter-arm medium, similar to what is found for other spiral galaxies in the local Universe. We observe that only the distributions of cloud mass surface densities and aspect ratio in the spiral arms show significant differences compared to those of the inter-arm medium; other observed differences appear instead to be driven by a distance bias. By comparing our results with simulations and observations of nearby galaxies, we conclude that the measured quantities would classify the Milky Way as a flocculent spiral galaxy, rather than as a grand-design one.